11:30 a.m.: North Carolina at Miami, ESPNU.
Noon: Utah at UCLA, Channel 11; Maryland at Virginia, Prime; Nevada at Nevada Las Vegas, TWCSN.
12:30 p.m.: Illinois at No. 25 Michigan, ESPN; Oklahoma State at Kansas, FS West; Bucknell at Harvard, CBSSN; Fresno State at No. 24 Boise State, NBCSN.
AFTERNOON
No. 4 Florida (5-0) at Vanderbilt (2-3)
3 p.m., ESPNU
This has all the makings for a Florida letdown as the Gators go on the road a week after upsetting Louisiana State in Gainesville. History suggests a Florida victory over Vanderbilt, as the Gators have won 21 straight in the SEC series. But South Carolina could vouch for how tough Vanderbilt is in Nashville after the Gamecocks squeaked out a 17-13 win earlier this season.
2:30 p.m.: Boston College at No. 12 Florida State, ESPN2.
3:30 p.m.: Colorado State at San Diego State, TWCSN.
4 p.m.: No. 11 USC at Washington, Channel 11; Texas Christian at Baylor, FS West; Kentucky at Arkansas, Prime.
EVENING
No. 3 South Carolina (6-0) at No. 9 Louisiana State (5-1)
5 p.m., ESPN
Now we find out: Is South Carolina, coming off a dominating 35-7 home win over Georgia, a legitimate national title contender? A two-week SEC road swing through LSU and Florida should answer that question. Now we find out: does LSU have anything more than a strong defense? The Tigers must win this game to make sure Alabama's Nov. 3 arrival in Baton Rouge has national implications for both schools.
No. 22 Texas A&M (4-1) vs. No. 23 Louisiana Tech (5-0) at Shreveport, La.
6 p.m. ESPNU
Hurricane Isaac forced the postponement of this game from Labor Day weekend, but now it's a good-looking matchup with national implications. Texas A&M's only loss came at home to Florida; undefeated Louisiana Tech has wins over Illinois and Virginia. A win for Louisiana Tech would give the Bulldogs an outside, but not impossible, chance to earn an automatic Bowl Championship Series bid.
5 p.m.: No. 8 Ohio State at Indiana, BTN; Southern Mississippi at Central Florida, CBSSN.
6 p.m.: Tennessee at No. 19 Mississippi State, ESPN2.
NIGHT
7:30 p.m.: California at Washington State, Pac-12.